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Top 12 Animations Where Depression Discovers the Struggle

Anime is often thought to be a form of escapism, showcasing fantastical realms and characters unlikely to appear in our world.

But many anime shows have strong connections to real life, themes, and emotions. These 12 Anime About Depression is no exception. 

Through stories about ordinary people struggling with inner demons, this article explores some of the best anime shows focusing on depression. 

From insights into its causes to sympathetic representations of a complex issue, each pick illuminates different aspects of mental health in an honest, accessible way.

If you’re looking for more than just Entertainment but meaningful insight into battling depression without judgment—this list is for you. 

Despite its dark setting and tough topics, these animated masterpieces offer solace and hope through realistic portraits that teach invaluable lessons worth remembering.


12. Paranoia Agent

Paranoia Agent

Paranoia Agent is an anime series from 2004 directed by Satoshi Kon. It follows a hopeless and disturbed Tokyo Police Detective, Keiichi Ikari, as he investigates mysterious cases in which people have been attacked by an unseen assailant wielding a baseball bat.

This mysterious figure is later revealed to be Lil’ Slugger—an apparently imaginary being created to represent the anxiety and depression that are overwhelming the characters in the show.

Through its narrative, Paranoia Agent cleverly examines how depression can create feelings of paranoia, isolation and fear while also providing hope that understanding and working through those emotions can help people overcome them.

The series has won numerous awards and is regarded as a masterpiece by fans around the world, who appreciate its unique storytelling style combined with its intelligence and insight into mental health issues.

11. Aoi Bungaku

Aoi Bungaku

Aoi Bungaku is a Japanese anime series of six entrancing stories that explore the fragile nature of depression. Following several characters struggling with depression, Aoi Bungaku guides viewers through highly personal journeys that illustrate a myriad of inner battles.

From loss to taboo desires, this series accurately portrays various mental health issues in an empathetic and thought-provoking manner. With solidly crafted animation, powerful soundtracks and intense scenes, the show takes its audience on a remarkable voyage.

Indeed, it is no surprise Aoi Bungaku has been commended for its insightful portrayal of depression, sure to evoke genuine sentiment from even the most jaded viewer.

Furthermore, detailed characterization allows viewers to connect emotionally with each protagonist’s story.

10. Narutaru


Narutaru, an iconic Japanese anime, is an unflinching look at depression. It follows the story of a young girl named Shiina Tamai who discovers strange creatures called Shadow Dragons that have arrived on Earth.

However, as she and her friends confront these creatures, they must unite to battle a far greater enemy – their despair and depression.

The story captures the difficulties of adolescence, showing its young protagonists tackling mental health issues in a deeply meaningful form – one that neither shies away from the realities of life nor sugarcoats it.

Narrated with heart-wrenching seriousness and backed by gripping visuals, this thought-provoking series is a must for anyone looking to escape into animation about depression, as it’s both entertaining and inspirational even when faced with dark topics.

9. Kara no Kyoukai

Kara no Kyoukai

Kara no Kyoukai” is an iconic anime about depression. The story follows Ryoji, a seemingly emotionless character with a dark past, as he confronts his inner demons and struggles to understand the meaning of life.

With its extremely rich visual quality and profound messages, “Kara no Kyoukai” has become a highly-ranked anime series by IMDb. Its intricate plot follows Ryoji along his journey while keeping us hooked through extreme suspense and powerful music.

Its acclaimed atmosphere brings thought-provoking themes of identity and existence, which lead characters on their personal paths as they find out what living truly means.

Throughout its episodes, it touches upon diverse emotions like despair and acceptance- all in an attempt to make sense of the suffering that everyone inevitably experiences in life.

8. The Tatami Galaxy

The Tatami Galaxy

Considered one of the greatest anime series about depression, “The Tatami Galaxy” is a masterpiece. Written by Masaaki Yuasa and debuted in 2010, this offbeat anime explores themes such as loneliness, regret, obsession and ennui.

The story revolves around an unnamed protagonist who rashly makes decisions that have negative consequences in his life – each decision he makes is represented by four alternate realities where he relives different versions of the same life in a tatami-mat room at university.

Attention to detail and stunning animation combine with poignant darkness to craft an unforgettable viewing experience.

Throughout the series, viewers watch as characters take control of their individual destinies while dealing with moments of despair and sorrow, creating an incredibly nuanced portrait of life for those whose minds struggle with depression.

7. Sayonara, Zetsubou-Sensei

Sayonara, Zetsubou-Sensei

Sayonara, Zetsubou-Sensei is an extremely entertaining and thoughtfully crafted anime about depression. It follows the gloomy teacher Nozomu who constantly views the world in a state of despair and has immense levels of stress to never reach his goals.

Despite it being a comedy, Sayonara, Zetsubou-Sensei offers great life lessons on how to triumph over loneliness and depression through its characters.

For instance, Nozomu learns to regulate his reactions to everyday stressors and is ultimately able to turn potential negative experiences into positive ones.

On the other hand, his students feel inspired by Nozomu’s words and attempt to apply them in developing their own coping mechanisms for dealing with depression.

The anime sends a powerful message that even if we can’t necessarily control our thoughts, we can always look at things from another perspective that is more optimistic.

6. Serial Experiments Lain

Serial Experiments Lain

Serial Experiments Lain is an anime about depression and its effects on the human psyche. It’s a cult classic in Japan that was produced by Triangle Staff and broadcasted on Tokyo TV from 1998 to 1999.

The story follows Lain Iwakura, a teenager who becomes emotionally isolated and confused as she watches people around her become obsessed with the new “Wired” technology that seems to be taking over their lives.

As Lain dives into the “Wired” network, she encounters mysteries related to her dead classmate’s suicide and soon discovers that alternate realities exist within the Wired.

Serial Experiment Lain has mesmerizing background music, surreal visuals, and imaginative plotlines- making it an apt fit for viewers looking for a thought-provoking anime about mental health.

5. The Black Rock Shooter (TV show)

Black Rock Shooter (TV series)

The Black Rock Shooter is one such anime that collaterally encourages people who are depressed and struggling with darkness.

This show tells the story of a teenage girl named Mato Kuroi and a creative being named Black Rock Shooter; together, they fight their inner demons and depression to show us what inner strength and courage look like.

It is depicted in such ways that it gives enough understanding of why sadness and anxiety can take over someone’s life and how it has an impact on their current situation. It gives us hope to realize our strength in the midst of all problems happening in the world.

Not only does it talk about facing depression, but it also deals mostly with teenage issues like those between family, friends, peers, social circle etc. The characters portrayed in this anime equally challenge mental health stigma, which portrays it as a relatable story for many.

Every single character is shown in different stages of depression, who will be able to identify themselves from every perspective shown by The Black Rock Shooter anime series, which might be encouraging for them at times of turmoil.

4. Colorful


Colorful, an anime movie about depression, has made a tremendous impact with its honest and sincere portrayal of a young man trying to understand and accept his struggling mental state. Though he first appears to be living a perfect life, his true self is soon revealed- one stuck in the depths of depression.

With minimal dialogue and immersive visuals, Colorful portrays delicate moments of pain and despair as the protagonist struggles to maintain his inner balance.

It really demonstrates how depression can affect even the most utopian person if they do not have adequate coping skills and emotional support.

As the story climaxes and our hero learns how to find hope in his own strength, Colorful shines a spotlight on why it’s so important for those who face mental challenges to talk about them and receive help from others.

Watching this anime helps viewers understand that although depression can appear overwhelming, guidance and support are always within reach.

3. Neon Genesis Evangelion

Neon Genesis Evangelion

Neon Genesis Evangelion” is an anime that explores themes related to depression in a visually captivating and narratively complex way.

It tells the story of a group of teenagers who are chosen by their government to pilot giant robots called Evangelions in order to protect the world from invading monsters known as Angels.

The characters’ struggles with mental illness and how they cope with it are masterfully portrayed, providing great insight into how society perceives emotional problems.

In particular, Shinji Ikari, the show’s lead protagonist, is highly relatable due to his internal strife over life and his fear of failure due to his lack of self-esteem.

Moreover, despite its fantastic universe setting, Neon Genesis Evangelion features grounded dialogue sequences between characters during which they confront deep emotional questions about living meaningful lives despite feelings of worthlessness and alienation.

2. Welcome to the NHK

Welcome to the NHK

If you are looking for an anime that explores the depths of depression, “Welcome to the NHK” is a great choice. It first premiered in 2006 and followed its protagonist Satou Tatsuhiro as he navigates his way through a severe depression.

This fantasy-thriller follows him as he struggles to find meaning in his life and works towards recovery with the help of a strange girl named Misaki, who claims she can help cure his hikikomori.

While the show likely won’t leave viewers feeling hopeful, it realistically portrays how hard those suffering from depression can be on themselves and highlights how difficult it can be to make even small steps towards betterment.

Featuring unique animation styles such as water-coloured backgrounds and extreme camera angles, this show has made quite a name for itself over the years.

1. Aku no Hana

Aku no Hana

Aku no Hana, sometimes known as The Flowers of Evil, is an anime series about a teenage boy in Tokyo who deals with depression.

The main character faces deep feelings of isolation and alienation from his peers and finds solace in the dark and dreary atmosphere that dominates the series.

Through its engaging and detailed visuals, Aku no Hana plunges viewers into the protagonist’s unique world of angst-ridden teenage emotions.

Beyond just being entertaining, however, Aku no Hana offers insight into the struggles faced by those around us who may be dealing with mental health issues.

It brings high school life to life in a troublingly realistic manner and provides opportunities for viewers to better understand what they or their loved ones are going through.


These 12 Anime About Depression explores the struggle of a wide variety of characters and their personal battle with depression. 

Through depictions of intersecting themes such as mental illness, trauma, death, and other difficult circumstances, anime fans have found these titles to be poignant explorations of humans dealing with great emotional stress. 

For those struggling personally or for those wanting to learn more about depression and how it affects people emotionally, these anime titles provide a unique window into the experience of individuals and their journeys. 

While there are much more anime out there that touch on themes related to depression, these 12 Anime About Depression provides an easily digestible set of varied entries that can give viewers an engaging set of stories to explore on the topic.

Patrick L.

Hey Internet, I am Patrick from New York. I love exploring Japanese culture and watching anime. I'm here to share my experience through character and anime recommendations. Kindly share your feedback on whether my articles piqued your interest.